Home - Products - Others - Other Targets - Pomalidomide-PEG4-C2-NH2 hydrochloride

Pomalidomide-PEG4-C2-NH2 hydrochloride

CAS No. 2357105-92-9

Pomalidomide-PEG4-C2-NH2 hydrochloride ( —— )

Catalog No. M28272 CAS No. 2357105-92-9

Pomalidomide-PEG4-C2-NH2 hydrochloride is a PEG-based PROTAC linker that can be used to synthesize PROTACs.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
10MG 46 Get Quote
25MG 77 Get Quote
50MG 125 Get Quote
100MG Get Quote Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    Pomalidomide-PEG4-C2-NH2 hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    Pomalidomide-PEG4-C2-NH2 hydrochloride is a PEG-based PROTAC linker that can be used to synthesize PROTACs.
  • Description
    Pomalidomide-PEG4-C2-NH2 hydrochloride is a PEG-based PROTAC linker that can be used to synthesize PROTACs.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    SOS1
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2357105-92-9
  • Formula Weight
    529.0
  • Molecular Formula
    C23H33ClN4O8
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3NCCOCCOCCOCCOCCN)=O.[H]Cl
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Ketcham JM, et al. Design and Discovery of MRTX0902, a Potent, Selective, Brain-Penetrant, and Orally Bioavailable Inhibitor of the SOS1:KRAS Protein-Protein Interaction. J Med Chem. 2022 Jul 28;65(14):9678-9690.
molnova catalog
related products
  • SAR131675(b)

    SAR131675 is an effective and specific VEGFR-3 inhibitor. It inhibited VEGFR-3 tyrosine kinase activity (IC50: 20 nmol/L) and VEGFR-3 autophosphorylation (IC50: 45 nmol/L) in HEK cells, respectively.

  • Benzylurea

    Benzylurea competitively inhibits dehydrogenase/cytokinin oxidase.

  • ML382

    ML382 is a potent and selective MrgX1 positive allosteric modulator(EC50 : 190 nM).ML382 enhances the ability of BAM8-22 to inhibit high-voltage-activated Ca2+ channels and attenuate spinal nociceptive transmission, both BAM8-22 and ML382 effectively attenuated evoked, persistent, and spontaneous pain without causing obvious side effects.?