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Pomalidomide-PEG4-C2-NH2 hydrochloride

CAS No. 2357105-92-9

Pomalidomide-PEG4-C2-NH2 hydrochloride( —— )

Catalog No. M28272 CAS No. 2357105-92-9

Pomalidomide-PEG4-C2-NH2 hydrochloride is a PEG-based PROTAC linker that can be used to synthesize PROTACs.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Pomalidomide-PEG4-C2-NH2 hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    Pomalidomide-PEG4-C2-NH2 hydrochloride is a PEG-based PROTAC linker that can be used to synthesize PROTACs.
  • Description
    Pomalidomide-PEG4-C2-NH2 hydrochloride is a PEG-based PROTAC linker that can be used to synthesize PROTACs.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    SOS1
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2357105-92-9
  • Formula Weight
    528.98
  • Molecular Formula
    C23H33ClN4O8
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 220 mg/mL (415.89 mM)
  • SMILES
    O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3NCCOCCOCCOCCOCCN)=O.[H]Cl
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Ketcham JM, et al. Design and Discovery of MRTX0902, a Potent, Selective, Brain-Penetrant, and Orally Bioavailable Inhibitor of the SOS1:KRAS Protein-Protein Interaction. J Med Chem. 2022 Jul 28;65(14):9678-9690.
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